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PUBBLICAZIONI

SCIENTIFICHE

2025

  • De Marco, A.; Baldassarro, V. A.; Cescatti, M.; Moretti, M.; Calzà, L.; Giardino, L.; Dondi, F.; Ferrari, M. G.; Gatta, P. P.; Parma, L.; Bonaldo, A. (2025) Effect of simulated prolonged heat wave on biometric performance and HSP70 synthesis in the striped venus clam Chamelea gallina. Aquaculture, 603, 1-10 doi: 10.1016/j.aquaculture.2025.742422 | ScienceDirect
  • Borjini, N.; Fernandez, M.; Giardino, L.; Sorokin, L.; Calzà, L. (2025) Pharmacological Inhibition of Microglial Proliferation Supports Blood-Brain Barrier Integrity in Experimental Autoimmune Encephalomyelitis. Cells 2025, 14(6):414. doi: 10.3390/cells14060414 | PubMed
  • Quadalti, C.; Moretti, M.; Ferrazzi, F.; Calzà, L.; Giardino, L; Baldassarro, V. A. (2025) Rat embryonic stem cell-based in vitro testing platform for mammalian embryo toxicology at pre- and post-implantation stages. Frontiers in Toxicology, 7:1561386. doi: 10.3389/ftox.2025.1561386 | PubMed
  • Baldassarro, V. A.; Baroncini, I.; Calzà, L.; Ciardulli, F.; Lorenzini, L.; Materazzi, F. G.; Merighi, F.; Quadalti, C.; Ricci, L.;Serafino, F.; Simoncini, L. (2025) Neurorehabilitation and white matter repair in traumatic spinal cord injury: a dialogue between clinical and preclinical studies. Frontiers in Neurology, 16:1532056. doi: 10.3389/fneur.2025.1532056 | PubMed

2024

  • Lorenzini, L.; Zanella, L.; Sannia, M.; Baldassarro, V. A.; Moretti, M.; Cescatti, M.; Quadalti, C.; . . . Calzà, L.; Giardino, L. (2024) Experimental colitis in young Tg2576 mice accelerates the onset of an Alzheimer’s-like clinical phenotype. Alzheimer’s Research & Therapy, 16(1):116.doi: 10.1186/s13195-024-01471-2 | PubMed
  • Baldassarro, V. A.; Alastra, G.; Cescatti, M.; Quadalti, C.; Lorenzini, L., Giardino, L.; Calzà, L. (2024) SARS-CoV-2-related peptides induce endothelial-to-mesenchymal transition in endothelial capillary cells derived from different body districts: focus on membrane (M) protein. Cell and Tissue Research, 397(3):241-262. doi: 10.1007/s00441-024-03900-y | PubMed
  • Palumbo, F. S.; Calligaris, M.; Calzà, L.; Fiorica, C.; Baldassarro, V. A.; Carreca, A. P.; Lorenzini, L.; Giuliani, A.; . . . Chinnici, C. M. (2024) Topical application of a hyaluronic acid-based hydrogel integrated with secretome of human mesenchymal stromal cells for diabetic ulcer repair. Regenerative Therapy, 26:520-532. doi: 10.1016/j.reth.2024.07.008 | PubMed
  • Noera, G.; Bertolini, A.; Calzà, L.; Gori, M.; Pitino, A.; D’Arrigo, G.; Egan, C. G.; Tripepi, G. Effect of early administration of tetracosactide on mortality and host response in critically ill patients requiring rescue surgery: a sensitivity analysis of the STOPSHOCK phase 3 randomized controlled trial. (2024) Military Medical Research, 11(1):56. doi: 10.1186/s40779-024-00555-2 | PubMed
  • Quadalti, C.; Sannia, M.; Humphreys, N. E.; Baldassarro, V. A.; Gurgone, A.; Ascolani, M.; Zanella, L.; Giardino, L.; . . . Lorenzini, L.; Calzà, L. (2024) A new knockin mouse carrying the E364X patient mutation for CDKL5 deficiency disorder: neurological, behavioral and molecular profiling. Heliyon, 10(21):e40165. doi: 10.1016/j.heliyon.2024.e40165 | PubMed

2023

  • Baldassarro, V. A.; Calzà, L.; Giardino, L.; De Marco, A.; Dondi, F.; Ferrari, M. G.; Bignami, G.; Parma, L.; Bonaldo, A. (2023) Prolonged heat waves reduce the condition index and alter the molecular parameters in the pacific oyster Crassostrea gigas. Fish & Shellfish Immunology, 133:108518. doi: 10.1016/j.fsi.2023.108518 | PubMed
  • Stanzani, A.; Sansone, A.; Brenna, C., Baldassarro, V. A.; Alastra, G.; Lorenzini, L.; . . . Calzà, L. (2023) Erythrocyte Plasma Membrane Lipid Composition Mirrors That of Neurons and Glial Cells in Murine Experimental In Vitro and In Vivo Inflammation. Cells 2023, 12(4):561. doi: 10.3390/cells12040561 | PubMed
  • Moretti, M.; Caraffi, R.; Lorenzini, L.; Ottonelli, I.; Sannia, M.; Alastra, G.; Baldassarro, V.A.; Giuliani, A.; Duskey, J.T.; Cescatti, M.; Ruozi, B.; Aloe, L.; Vandelli, M.A.; Giardino, L.; Tosi, G.; Calzà, L. (2023) “Combo” Multi-Target Pharmacological Therapy and New Formulations to Reduce Inflammation and Improve Endogenous Remyelination in Traumatic Spinal Cord Injury. Cells 2023, (9):1331. doi: 10.3390/cells12091331 | PubMed
  • Baldassarro, V. A.; Cescatti, M.; Rocco, M. L.; Aloe, L.; Lorenzini, L.; Giardino, L.; Calzà, L. (2023) Nerve growth factor promotes differentiation and protects the oligodendrocyte precursor cells from in vitro hypoxia/ischemia. Frontiers in Neuroscience, 17:1111170. doi: 10.3389/fnins.2023.1111170 | PubMed
  • Baldassarro, V. A.; Giraldi, V.; Giuliani, A.; Moretti, M.; Pagnotta, G.; Flagelli, A.; . . . Calzà, L. (2023) Poly(l-lactic acid) Scaffold Releasing an α4β1 Integrin Agonist Promotes Nonfibrotic Skin Wound Healing in Diabetic Mice. ACS Applied Bio Materials, 6(1):296-308. doi: 10.1021/acsabm.2c00890 | PubMed 
  • Baldassarro, V. A.; Perut, F.; Cescatti, M.; Pinto, V.; Fazio, N.; Alastra, G.; Parziale, V.; Bassotti, A.; Fernandez, M.; Giardino, L.; Baldini, N.; Calzà, L. (2023) Intra-individual variability in the neuroprotective and promyelinating properties of conditioned culture medium obtained from human adipose mesenchymal stromal cells. Stem Cell Research & Therapy, 4(1):128. doi: 10.1186/s13287-023-03344-1 | PubMed
  • Baldassarro, V. A.; Quadalti, C.; Runfola, M.; Manera, C.; Rapposelli, S.; Calzà, L. (2023) Synthetic Thyroid Hormone Receptor-β Agonists Promote Oligodendrocyte Precursor Cell Differentiation in the Presence of Inflammatory Challenges. Pharmaceuticals 2023, 16(9):1207. doi: 10.3390/ph16091207 | PubMed 
  • Baldassarro, V. A.; Alastra, G.; Lorenzini, L.; Giardino, L.; Calzà, L. (2023) Photobiomodulation at Defined Wavelengths Regulates Mitochondrial Membrane Potential and Redox Balance in Skin Fibroblasts. Oxidative Medicine and Cellular Longevity, 2023:7638223. doi: 10.1155/2023/7638223 | PubMed
  • Ferroni, L.; … Giuliani, A.; Calzà, L.; … (2023) Stem cell-derived small extracellular vesicles embedded into methacrylated hyaluronic acid wound dressings accelerate wound repair in a pressure model of diabetic ulcer. Journal of Nanobiotechnology, 21(1):469. doi: 10.1186/s12951-023-02202-9 | PubMed 
  • Sabattini, S.; Baldassarro, V. A.; Zaccone, R.; Calzà, L.; Giardino, L,; Vascellari, M.; Lorenzini, L.; Moretti, M.; Marconato, L. (2023) Dysregulated miRNAs in a canine model of haemangiosarcoma metastatic to the brain. Veterinary and Comparative Oncology, 22(1):70-77. doi: 10.1111/vco.12949 | PubMed

2022

  • Bianco, F.; Lattanzio, G.; Lorenzini, L.; Mazzoni, M.,;Clavenzani, P.; Calzà, L.; . . . De Giorgio, R. (2022) Enteric neuromyopathies: Highlights on genetic mechanisms underlying chronic intestinal pseudo-obstruction. Biomolecules, 12(12) doi:10.3390/biom12121849 | PubMed
  • Merlo, B.; Baldassarro, V. A.; Flagelli, A.; Marcoccia, R.; Giraldi, V.; Focarete, M. L.; Giacomini, D.; Iacono, E. (2022) Peptide Mediated Adhesion to Beta-Lactam Ring of Equine Mesenchymal Stem Cells: A Pilot Study. Animals 2022, 12(6):734. doi: 10.3390/ani12060734 | PubMed
  • Ellero, N.; Lanci, A.; Baldassarro, V. A.; Alastra, G.; Mariella, J.; Cescatti, M.; Giardino, L.; Castagnetti, C. (2022) Study on NGF and VEGF during the Equine Perinatal Period-Part 2: Foals Affected by Neonatal Encephalopathy. Veterinary Sciences 2022, 9(9):459. doi: 10.3390/vetsci9090459 | PubMed
  • Baldassarro, V.; Stanzani, A.; Giardino, L.; Calzà, L.; Lorenzini, L. (2022) Neuroprotection and neuroregeneration: roles for the white matter. Neural Regeneration Research, 17(11), 2376-2380. doi:10.4103/1673-5374.335834 | PubMed
  • Baldassarro, V. A.; Lorenzini, L.; Giuliani, A.; Cescatti, M.; Alastra, G.; Pannella, M.; . . . Giardino, L. (2022) Molecular mechanisms of skin wound healing in non-diabetic and diabetic mice in excision and pressure experimental wounds. Cell and Tissue Research, 388(3), 595-613. doi:10.1007/s00441-022-03624-x | PubMed
  • Bianco, F.; Bonora, E.; Lattanzio, G.; Clavenzani, P.; Guarino, M.; Mazzoni, M.; . . . De Giorgio, R. (2022) Clinical and Pathological Features of Severe Gut Dysmotility. 1383:9-17. doi: 10.1007/978-3-031-05843-1_2 | PubMed
  • Troia, R.; Sabetti, M. C.; Crosara, S.; Quintavalla, S.; Romito, G.; Mazzoldi, C.; Fidanzio, F.; Cescatti, M.; Bertazzolo, W.; Giunti, M.; Dondi, F. (2022) Evaluation of urinary neutrophil gelatinase-associated lipocalin to detect renal tubular damage in dogs with stable myxomatous mitral valve disease. Journal of Veterinary Internal Medicine, 36(6):2053-2062. doi: 10.1111/jvim.16503 | PubMed
  • Bertini, F.; Allevi, D.; Lutero, G.; Calza, L.; Montesi, D. (2022) A cross-language dementia classifier: A preliminary study. Paper presented at the 2022 IEEE International Workshop on Metrology for Extended Reality, Artificial Intelligence and Neural Engineering (MetroXRAINE). MetroXRAINE 2022 – Proceedings, 438-443. doi:10.1109/MetroXRAINE54828.2022.9967558 | IEEE Xplore

2021

  • Flagelli, A.; Candini, O.; Frabetti, S.; Dominici, M.; Giardino, L.; Calzà, L.; Baldassarro, V. A. (2021). A Novel Three-Dimensional Culture Device Favors a Myelinating Morphology of Neural Stem Cell-Derived Oligodendrocytes. Frontiers in Cell and Developmental Biology, 9:759982. doi: 10.3389/fcell.2021.759982 | PubMed
  • De Santis, I.; Lorenzini, L.; Moretti, M.; Martella, E.; Lucarelli, E.; Calzà, L.; Bevilacqua, A. (2021). Co-Density Distribution Maps for Advanced Molecule Colocalization and Co-Distribution Analysis. Sensors, 21(19):6385. doi: 10.3390/s21196385 | PubMed
  • Baldassarro, V. A.; Sanna, M.; Bighinati, A.; Sannia, M., Gusciglio, M., Giardino, L., .  Calzà, L. (2021). A Time-Course Study of the Expression Level of Synaptic Plasticity-Associated Genes in Un-Lesioned Spinal Cord and Brain Areas in a Rat Model of Spinal Cord Injury: A Bioinformatic Approach. International Journal of Molecular Sciences 2021, 22(16):8606. doi: 10.3390/ijms22168606 | PubMed
  • Alastra, G.; Aloe, L.; Baldassarro, V. A.; Calzà, L.; Cescatti, M.; Duskey, J. T.; . . . Tosi, G. (2021). Nerve Growth Factor Biodelivery: A Limiting Step in Moving Toward Extensive Clinical Application? Frontiers in Neuroscience, 15:695592. doi: 10.3389/fnins.2021.695592 | PubMed 
  • Dolci, L. S.; Perone, R. C.; Di Gesù, R.; Kurakula, M.; Gualandi, C.; Zironi, E.; Gazzotti, T.; Tondo, M. T.; Pagliuca, G.; Gostynska, N.; Baldassarro, V. A.; Cescatti, M.; Giardino, L.; Focarete, M. L.; Calzà, L.; Passerini, N.; Bolognesi, M. L. (2021) Design and In Vitro Study of a Dual Drug-Loaded Delivery System Produced by Electrospinning for the Treatment of Acute Injuries of the Central Nervous System. Pharmaceutics 2021, 13(6):848. doi: 10.3390/pharmaceutics13060848 | PubMed
  • Bianco, F.; Lattanzio, G.; Lorenzini, L.; Diquigiovanni, C.; Mazzoni, M.; Clavenzani, P.; De Giorgio, R. (2021). Novel understanding on genetic mechanisms of enteric neuropathies leading to severe gut dysmotility. European Journal of Histochemistry, 65(s1):3289. doi: 10.4081/ejh.2021.3289 | PubMed 
  • Bighinati, A.; Khalajzeyqami, Z.; Baldassarro, V. A.; Lorenzini, L.; Cescatti, M.; Moretti, M.; . . . Calzà, L. (2021). Time-Course Changes of Extracellular Matrix Encoding Genes Expression Level in the Spinal Cord Following Contusion Injury-A Data-Driven Approach. International Journal of Molecular Sciences 2021, 22(4):1744. doi: 10.3390/ijms22041744 | PubMed
  • Baldassarro, V.; Giardino, L.; Calzà, L. (2021). Oligodendrocytes in a dish for the drug discovery pipeline: The risk of oversimplification. Neural Regeneration Research,
    16(2):291-293. doi: 10.4103/1673-5374.290888 | PubMed
  • Baldassarro, V. A.; Lorenzini, L.; Bighinati, A.; Giuliani, A.; Alastra, G.; Pannella, M.;  .Calzà, L. (2021). NGF and Endogenous Regeneration: From Embryology Toward Therapies. Advances in Experimental Medicine and Biology, 1331:51-63. doi: 10.1007/978-3-030-74046-7_5 | PubMed
  • Rocco, M. L.; Calzà, L.; Aloe, L. (2021). NGF and Retinitis Pigmentosa: Structural and Molecular Studies. Advances in Experimental Medicine and Biology, 1331:255-263. doi: 10.1007/978-3-030-74046-7_17 | PubMed
  • Baldassarro, V. A.; Flagelli, A.; Sannia, M.; Calzà, L. (2021) Nuclear receptors and differentiation of oligodendrocyte precursor cells. Advances in Experimental Medicine and Biology, 116:389-407. doi: 10.1016/bs.vh.2021.02.002 | PubMed 

2020

  • Lovecchio, J.; Pannella, M.; Giardino, L.; Calzà, L., Giordano, E. (2020) A dynamic culture platform enhances the efficiency of the 3D HUVEC-based tube formation assay. Biotechnology and Bioengineering, 117(3):789-797. doi: 10.1002/bit.27227 | PubMed
  • Gostynska, N.; Pannella, M.; Rocco, M. L.; Giardino, L.; Aloe, L.; Calzà, L. (2020)The pleiotropic molecule NGF regulates the in vitro properties of fibroblasts, keratinocytes, and endothelial cells: implications for wound healing. American Journal of Physiology. Cell Physiology, 318(2):C360-C371. doi: 10.1152/ajpcell.00180.2019 | PubMed
  • Lorenzini, L,; Fernandez, M.; Baldassarro, V. A.; Bighinati, A.; Giuliani, A.; Calzà, L.; Giardino, L. (2020) White Matter and Neuroprotection in Alzheimer’s Dementia. Molecules 2020,
    25(3):503. doi: 10.3390/molecules25030503 | PubMed 
  • Tschon, M.; Salamanna, F.; Martini, L.; Giavaresi, G., Lorenzini, L.; Calzà, L.; Fini, M. (2020) Boosting the Intra-Articular Efficacy of Low Dose Corticosteroid through a Biopolymeric Matrix: An In Vivo Model of Osteoarthritis. Cells 2020, 9(7):1571. doi: 10.3390/cells9071571 | PubMed
  • Baldassarro, V. A.; Giardino, L.; Calzà, L. (2020) Oligodendrocytes in a dish for the drug discovery pipeline: the risk of oversimplification. Neural Regeneration Research,16(2):291-293. doi: 10.4103/1673-5374.290888 | PubMed
  • Baldassarro, V. A.; Bighinati, A.; Sannia, M.; Giardino, L.; Calzà, L. (2020) Brain susceptibility to hypoxia/hypoxemia and metabolic dysfunction in Alzheimer’s disease: insights from animal and in vitro models. Genetics, Neurology, Behavior, and Diet in Dementia, Vol. 2 (pp. 407-422), doi.org/10.1016/B978-0-12-815868-5.00026-8 | ScienceDirect
  • Bighinati, A.; Focarete, M. L.; Gualandi, C.; Pannella, M.; Giuliani, A.; Beggiato, S.; Ferraro, L.; Lorenzini, L; Giardino, L.; Calzà, L. (2020) Improved Functional Recovery in Rat Spinal Cord Injury Induced by a Drug Combination Administered with an Implantable Polymeric Delivery System. Journal of Neurotrauma, 37(15):1708-1719. doi: 10.1089/neu.2019.6949 | PubMed
  • Fernández, M.; Baldassarro, V. A.; Capirossi, R.; Montevecchi, R.; Bonavita, J.; Cescatti, M.; Giovannini, T.; Giovannini, G.; Uneddu, M.; Giovanni, G.; Giardino, L.; Calzà, L. (2020) Possible Strategies to Optimize a Biomarker Discovery Approach to Correlate with Neurological Outcome in Patients with Spinal Cord Injury: A Pilot Study. Journal of Neurotrauma, 37(3):431-440. doi: 10.1089/neu.2018.6362 | PubMed
  • Calzà, L.; Gagliardi, G.; Favretti Rossini, R.; Tamburini, F. (2020) Linguistic Features of Clients and Counselors for Early Detection of Mental Health Issues in Online Text-based Counseling. Annual International Conference of the IEEE Engineering in Medicine and Biology Society,2022:2668-2671. doi: 10.1109/EMBC48229.2022.9871408 | PubMed
  • Giuliani, A.; Lorenzini, L.; Baldassarro, V. A.; Pannella, M.; Cescatti, M.; Fernandez, M.; Alastra, G.; Flagelli, A.; Villetti, G.; Imbimbo, B. P.; Giardino, L.; Calzà, L. (2020) Effects of Topical Application of CHF6467, a Mutated Form of Human Nerve Growth Factor, on Skin Wound Healing in Diabetic Mice. Journal of Pharmacology and Experimental Therapeutics,
    375(2):317-331. doi: 10.1124/jpet.120.000110 | PubMed
  • Capirossi, R.; Piunti, B.; Fernández, M.; Maietti, E.; Rucci, P.; Negrini, S.; Giovannini, T.; Kiekens, C.; Calzà, L. (2020) Early CSF Biomarkers and Late Functional Outcomes in Spinal Cord Injury. A Pilot Study. International Journal of Molecular Sciences 2020, 21(23):9037. doi: 10.3390/ijms21239037 | PubMed
  • Fernández, M.; Pannella, M.; Baldassarro, V. A.; Flagelli, A.; Alastra, G.; Giardino, L.; Calzà, L. (2020) Thyroid Hormone Signaling in Embryonic Stem Cells: Crosstalk with the Retinoic Acid Pathway. International Journal of Molecular Sciences 2020, 21(23):8945. doi: 10.3390/ijms21238945 | PubMed

2019

  • Giuliani, A.; Sivilia, S.; Baldassarro, V. A.; Gusciglio, M.; Lorenzini, L.; Sannia, M.; Calzà, L.; Giardino, L. (2019) Age-related changes of the neurovascular unit in the cerebral cortex of Alzheimer’s disease and age-matching wild-type mouse models: a neuroanatomical and molecular study. Journal of Neuropathology and Experimental Neurology, 78(2):101-112. doi: 10.1093/jnen/nly125 | PubMed
  • Baldassarro, V. A.; Krężel, W.; Fernández, M.; Schuhbaur, B.; Giardino, L., Calzà L. (2019) The role of nuclear receptors in the differentiation of oligodendrocyte precursor cells derived from fetal and adult neural stem cells. Stem Cell Research, 37:101443. doi: 10.1016/j.scr.2019.101443 | PubMed
  • Diquigiovanni, C.; Bergamini, C.; Diaz, R.; Liparulo, I.; Bianco, F.; Masin, L.; Baldassarro, V. A.; . . . (2019) A novel mutation in SPART gene causes a severe neurodevelopmental delay due to mitochondrial dysfunction with complex I impairments and altered pyruvate metabolism. FASEB Journal, 33(10):11284 11302. doi: 10.1096/fj.201802722R | PubMed
  • Bernardini, C.; Bertocchi, M.; Zannoni, A.; Salaroli, R.; Tubon, I.; Dothel, G.; Fernandez, M.; Bacci, M. L.; Calzà, L.; Forni, M. (2019) Constitutive and LPS-stimulated secretome of porcine Vascular Wall-Mesenchymal Stem Cells exerts effects on in vitro endothelial angiogenesis. BMC Veterinary Research, 15(1):123. doi: 10.1186/s12917-019-1873-1 | PubMed
  • Borjini, N.; Sivilia, S.; Giuliani, A.; Fernandez, M.; Giardino, L.; Facchinetti, F.; Calzà, L. (2019) Potential biomarkers for neuroinflammation and neurodegeneration at short and long term after neonatal hypoxic-ischemic insult in rat. Journal of Neuroinflammation, 16(1):194. doi: 10.1186/s12974-019-1595-0| PubMed 

2018

  • Pannella, M.; Giardino, L.; Calzà, L.; Fernández, M. (2018) Growth and Neurotrophic Factors in Embryonic Stem Cells. Methods in Molecular Biology, 1727:275-294. doi: 10.1007/978-1-4939-7571-6_21 | PubMed
  • Baldassarro, V. A.; Marchesini, A.; Facchinetti, F.; Villetti, G.; Calzà, L.; Giardino, L. (2018) Cell death in pure-neuronal and neuron-astrocyte mixed primary culture subjected to oxygen-glucose deprivation: The contribution of poly(ADP-ribose) polymerases and caspases. Microchemical Journal, Volume 136 (pp. 215-222). doi.org/10.1016/j.microc.2016.11.008 | ScienceDirect
  • Giuliani, A.; Balducci, A. G.; Zironi, E.; Colombo, G.; Bortolotti, F.; Lorenzini, L.; Galligioni, V.; Pagliuca, G.; Scagliarini, A.; Calzà, L.; Sonvico, F. (2018) In vivo nose-to-brain delivery of the hydrophilic antiviral ribavirin by microparticle agglomerates. Drug Delivery, 25(1):376-387. doi: 10.1080/10717544.2018.1428242 | PubMed
  • Calzà, L.; Baldassarro V. A.; Fernandez, M.; Giuliani, A.; Lorenzini, L.; Giardino, L. (2018) Thyroid Hormone and the White Matter of the Central Nervous System: From Development to Repair. Vitamins and Hormones, 06:253-281. doi: 10.1016/bs.vh.2017.04.003 | PubMed
  • Beltrami, D.; Gagliardi, G.; Rossini Favretti, R.; Ghidoni, E.; Tamburini, F.; Calzà, L. (2018) Speech Analysis by Natural Language Processing Techniques: A Possible Tool for Very Early Detection of Cognitive Decline? Frontiers in Aging Neuroscience,
    10:369. doi: 10.3389/fnagi.2018.00369 | PubMed

2017

  • Baldassarro, V. A.; Marchesini, A.; Giardino, L.; Calzà, L. (2017)  Vulnerability of primary neurons derived from Tg2576 Alzheimer mice to oxygen and glucose deprivation: role of intraneuronal amyloid-β accumulation and astrocytes. Disease Models & Mechanisms, 10(5):671-678. doi: 10.1242/dmm.028001 | PubMed
  • Calzà, L.; Baldassarro, V. A.; Fernandez, M.; Giuliani, A.; Lorenzini, L.; Giardino, L. (2017) Thyroid Hormone and the White Matter of the Central Nervous System: From Development to Repair. Vitamins and Hormones,106:253-281. doi: 10.1016/bs.vh.2017.04.003 | PubMed
  • Stagni, F.; Raspanti, A.; Giacomini, A.; Guidi, S.; Emili, M.; Ciani, E.; Giuliani, A.; Bighinati, A.; Calzà, L.; Magistretti, J.; Bartesaghi, R. (2017) Long-term effect of neonatal inhibition of APP gamma-secretase on hippocampal development in the Ts65Dn mouse model of Down syndrome. Neurobiology of Disease,
    103:11-23. doi: 10.1016/j.nbd.2017.03.012 | PubMed
  • Baldassarro, V. A.; Marchesini, A.; Giardino, L.; Calzà, L. (2017) PARP activity and inhibition in fetal and adult oligodendrocyte precursor cells: effect on cell survival and differentiation. Stem Cell Research, 22:54-60. doi: 10.1016/j.scr.2017.05.011 | PubMed
  • Pannella, M.; Giardino, L.; Calzà, L.; Fernández, M. (2017) Growth and Neurotrophic Factors in Embryonic Stem Cells, Methods in Molecular Biology, 1727:275-294. doi: 10.1007/978-1-4939-7571-6_21 | PubMed 

2016

  • Lorenzini, L.; Giuliani, A.; Sivilia, S.; Baldassarro, V. A.; Fernandez, M.; Margotti, M. L.; Giardino, L.; Fontani, V.; Rinaldi, S.; Calzà, L. (2016) REAC technology modifies pathological neuroinflammation and motor behaviour in an Alzheimer’s disease mouse model. Scientific Reports, 6:35719. doi: 10.1038/srep35719 | PubMed
  • Borjini, N.; Fernández, M.; Giardino, L.; Calzà, L. (2016) Cytokine and chemokine alterations in tissue, CSF, and plasma in early presymptomatic phase of experimental allergic encephalomyelitis (EAE), in a rat model of multiple sclerosis. Journal of Neuroinflammation, 13(1):291. doi: 10.1186/s12974-016-0757-6 | PubMed
  • Rubagotti, S.; Croci, S.; Ferrari, E.; Iori, M.; Capponi, P. C.; Lorenzini, L.; Calzà, L.; Versari, A.; Asti, M. (2016) Affinity of (nat/68)Ga-Labelled Curcumin and Curcuminoid Complexes for β-Amyloid Plaques: Towards the Development of New Metal-Curcumin Based Radiotracers. International Journal of Molecular Sciences 2016, 17(9):1480. doi: 10.3390/ijms17091480 | PubMed
  • Baldassarro, V. A.; Dolci, L. S.; Mangano, C.; Giardino, L.; Gualandi, C.; Focarete, M. L.; Calzà, L. (2016) In Vitro Testing of Biomaterials for Neural Repair: Focus on Cellular Systems and High-Content Analysis. BioResearch Open Access, 5(1):201-11. doi: 10.1089/biores.2016.0025 | PubMed
  • Fernández, M.; Baldassarro, V. A.; Sivilia, S.; Giardino, L.; Calzà, L. (2016) Inflammation severely alters thyroid hormone signaling in the central nervous system during experimental allergic encephalomyelitis in rat: Direct impact on OPCs differentiation failure. Glia, 64(9):1573-89. doi: 10.1002/glia.23025 | PubMed
  • Sivilia, S.; Mangano, C.; Beggiato, S.; Giuliani, A.; Torricella, R.; Baldassarro, V. A.; Fernandez, M.; Lorenzini, L.; Giardino, L.; Borelli, A. C.; Ferraro, L.; Calzà, L. (2016) CDKL5 knockout leads to altered inhibitory transmission in the cerebellum of adult mice. Genes, Brain, and Behavior, 15(5):491-502. doi: 10.1111/gbb.12292 | PubMed
  • Borroto-Escuela, D. O.; Wydra, K.; Pintsuk, J.; Narvaez, M.; Corrales, F.; Zaniewska, M.; Agnati, L. F.; Franco, R.; Tanganelli, S.; Ferraro, L.; Filip, M.; Fuxe, K. (2016) Understanding the Functional Plasticity in Neural Networks of the Basal Ganglia in Cocaine Use Disorder: A Role for Allosteric Receptor-Receptor Interactions in A2A-D2 Heteroreceptor Complexes. Neural Plasticity, 2016:4827268. doi: 10.1155/2016/4827268 | PubMed
  • Barbieri, M.; Ossato, A.; Canazza, I.; Trapella, C.; Borelli, A. C.; Beggiato, S.; Rimondo, C.; Serpelloni, G.; Ferraro, L.; Marti, M. (2016) Synthetic cannabinoid JWH-018 and its halogenated derivatives JWH-018-Cl and JWH-018-Br impair Novel Object Recognition in mice: Behavioral, electrophysiological and neurochemical evidence. Neuropharmacology, 109:254-269. doi: 10.1016/j.neuropharm.2016.06.027 | PubMed
  • Borroto-Escuela D. O.; Pintsuk, J.; Schäfer, T.; Friedland, K.; Ferraro, L.; Tanganelli, S.; Liu, F.; Fuxe, K. (2016) Multiple D2 heteroreceptor complexes: new targets for treatment of schizophrenia. Therapeutic Advances in Psychopharmacology, 6(2):77-94. doi: 10.1177/2045125316637570 | PubMed
  • Beggiato, S.; Tomasini, M. C.; Borelli, A. C.; Borroto-Escuela, D.O.; Fuxe, K.; Antonelli, T.; Tanganelli, S.; Ferraro, L. (2016) Functional role of striatal A2A, D2, and mGlu5 receptor interactions in regulating striatopallidal GABA neuronal transmission. Journal of Neurochemistry, 2016, 38(2):254-64. doi: 10.1111/jnc.13652 | PubMed
  • Ferraro, L.; Tiozzo Fasiolo, L.; Beggiato, S.; Borelli, A. C.; Pomierny-Chamiolo, L.; Frankowska, M.; Antonelli, T.; Tomasini, M. C.; Fuxe, K.; Filip, M. (2016) Neurotensin: A role in substance use disorder? Journal of Psychopharmacology, 30(2):112-27. doi: 10.1177/0269881115622240 | PubMed
  • Chiodi, V.; Ferrante, A.; Ferraro, L.; Potenza, R. L.; Armida, M.; Beggiato, S.; Pèzzola, A.; Bader, M.; Fuxe, K.; Popoli, P.; Domenici, M. R. (2016) Striatal adenosine-cannabinoid receptor interactions in rats over-expressing adenosine A2A receptors. Journal of Neurochemistry, 136(5):907-17. doi: 10.1111/jnc.13421 | PubMed
  • Tomasini, M. C.; Borelli A. C.; Beggiato, S.; Tanganelli, S.; Loche, A.; Cacciaglia, R.; Ferraro, L.; Antonelli, T. (2016) GET73 Prevents Ethanol-Induced Neurotoxicity in Primary Cultures of Rat Hippocampal Neurons. Alcohol and Alcoholism,
    51(2):128-35. doi: 10.1093/alcalc/agv094 | PubMed

2015

  • Rinaldi, S.; Calzà, L.; Giardino, L.; Biella, G. E.; Zippo, A. G.; Fontani, V. (2015) Radio electric asymmetric conveyer: a novel neuromodulation technology in Alzheimer’s and other neurodegenerative diseases. Frontiers in Psychiatry, 6:22. doi: 10.3389/fpsyt.2015.00022 | PubMed
  • Zaniboni, A.; Bernardini, C.; Bertocchi, M.; Zannoni, A.; Bianchi, F.; Avallone, G.; Mangano, C.; Sarli, G.; Calzà, L.; Bacci, M. L.; Forni, M. (2015) In vitro differentiation of porcine aortic vascular precursor cells to endothelial and vascular smooth muscle cells. American Journal of Physiology. Cell Physiology, 309(5):C320-31. doi: 10.1152/ajpcell.00049.2015 | PubMed
  • Calzà, L.; Fernández, M.; Giardino, L. (2015) Role of the Thyroid System in Myelination and Neural Connectivity. Comprehensive Physiology, 5(3):1405-21. doi: 10.1002/cphy.c140035 | PubMed
  • Tomasini, M. C.; Borelli, A. C.; Beggiato, S.; Ferraro, L.; Cassano, T.; Tanganelli, S.; Antonelli, T. (2015) Differential Effects of Palmitoylethanolamide against Amyloid-β Induced Toxicity in Cortical Neuronal and Astrocytic Primary Cultures from Wild-Type and 3xTg-AD Mice. Journal of Alzheimer’s Disease, 46(2):407-21. doi: 10.3233/JAD-143039 | PubMed
  • Giuliani, A.; Lorenzini, L.; Alessandri, M.; Torricella, R.; Baldassarro, V. A.; Giardino, L.; Calzà, L. (2015) In vitro exposure to very low-level laser modifies expression level of extracellular matrix protein RNAs and mitochondria dynamics in mouse embryonic fibroblasts. BMC Complementary and Alternative Medicine, 15:78. doi: 10.1186/s12906-015-0593-8 | PubMed
  • Porrini, V.; Lanzillotta, A.; Branca, C.; Benarese, M.; Parrella, E.; Lorenzini, L.; Calzà, L.; Flaibani, R.; Spano, P. F.; Imbimbo, B. P; Pizzi, M. (2015) CHF5074 (CSP-1103) induces microglia alternative activation in plaque-free Tg2576 mice and primary glial cultures exposed to beta-amyloid. Neuroscience, 302:112-20. doi: 10.1016/j.neuroscience.2014.10.029 | PubMed

2014

  • Rinaldi, S.; Calzà, L.; Giardino, L.; Biella, G. E., Zippo, A. G.; Fontani, V. (2014) Radio electric asymmetric conveyer: a novel neuromodulation technology in Alzheimer’s and other neurodegenerative diseases. Frontiers in Psychiatry,
    6:22. doi: 10.3389/fpsyt.2015.00022 | PubMed
  • Tomasini, M. C.; Borelli, A. C.; Beggiato, S.; Ferraro, L.; Cassano, T.; Tanganelli, S.; Antonelli, T. (2014) Differential Effects of Palmitoylethanolamide against Amyloid-β Induced Toxicity in Cortical Neuronal and Astrocytic Primary Cultures from Wild-Type and 3xTg-AD Mice. Journal of Alzheimer’s Disease,
    46(2):407-21. doi: 10.3233/JAD-143039 | PubMed
  • Porrini, V.; Lanzillotta, A.; Branca, C.; Benarese, M.; Parrella, E.; Lorenzini, L.; Calzà, L.; Flaibani, R.; Spano, P. F.; Imbimbo, B. P.; Pizzi, M. (2014) CHF5074 (CSP-1103) induces microglia alternative activation in plaque-free Tg2576 mice and primary glial cultures exposed to beta-amyloid. Neuroscience,
    302:112-20. doi: 10.1016/j.neuroscience.2014.10.029 | PubMed
  • Paradisi, M.; Alviano, F.; Pirondi, S.; Lanzoni, G.; Fernandez, M.; Lizzo, G.; Giardino, L.; Giuliani, A.; Costa, R.; Marchionni, C.; Bonsi, L.; Calza, L. (2014) Human mesenchymal stem cells produce bioactive neurotrophic factors: source, individual variability and differentiation issues. International Journal of Immunopathology and Pharmacology, 27(3):391-402. doi: 10.1177/039463201402700309 | PubMed
  • Alessandri, M.; Lizzo, G.; Gualandi, C.; Mangano, C.; Giuliani, A.; Focarete, M. L.; Calzà, L. (2014) Influence of biological matrix and artificial electrospun scaffolds on proliferation, differentiation and trophic factor synthesis of rat embryonic stem cells. Matrix Biology, 3:68-76. doi: 10.1016/j.matbio.2013.08.001 | PubMed
  • Fuchs, C.; Trazzi, S.; Torricella, R.; Viggiano, R.; De Franceschi, M.; Amendola, E.; Gross, C.;, Calzà, L.; Bartesaghi, R.; Ciani, E. (2014) Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling. Neurobiology of Disease, 70(100):53-68. doi: 10.1016/j.nbd.2014.06.006 | PubMed
  • Branca, C.; Sarnico, I.; Ruotolo, R.; Lanzillotta, A.; Viscomi, A. R.; Benarese, M., Porrini, V.; Lorenzini, L.; Calzà, L.; Imbimbo, B. P.; Ottonello, S.; Pizzi, M. (2014) Pharmacological targeting of the β-amyloid precursor protein intracellular domain. Scientific Reports, 4:4618. doi: 10.1038/srep04618 | PubMed
  • Beggiato, S.; Giuliani, A.; Sivilia, S.; Lorenzini, L.; Antonelli, T.; Imbimbo, B. P.; Giardino, L.; Calzà, L.; Ferraro, L. (2014) CHF5074 and LY450139 sub-acute treatments differently affect cortical extracellular glutamate levels in pre-plaque Tg2576 mice. Neuroscience, 266:13-22. doi: 10.1016/j.neuroscience.2014.01.065 | PubMed
  • Guidi, S.; Stagni, F.; Bianchi, P.; Ciani, E.; Giacomini, A.; De Franceschi, M.; Moldrich, R.; Kurniawan, N.; Mardon, K.; Giuliani, A.; Calzà, L.; Bartesaghi, R. (2014) Prenatal pharmacotherapy rescues brain development in a Down’s syndrome mouse model. Brain, 137(Pt 2):380-401. doi: 10.1093/brain/awt340 | PubMed
  • Zaniboni, A.; Bernardini, C.; Alessandri, M.; Mangano, C.; Zannoni, A.; Bianchi, F.; Sarli, G.; Calzà, L.; Bacci, M. L.; Forni, M. (2014) Cells derived from porcine aorta tunica media show mesenchymal stromal-like cell properties in in vitro culture. American Journal of Physiology. Cell Physiology. 306(4):C322-33. doi: 10.1152/ajpcell.00112.2013 | PubMed
  • Beggiato, S.; Antonelli, T.; Tomasini, M. C.; Borelli, A. C.; Agnati, L. F.; Tanganelli, S.; Fuxe, K.; Ferraro, L. (2014) Adenosine A2A-D2 receptor-receptor interactions in putative heteromers in the regulation of the striato-pallidal gaba pathway: possible relevance for parkinson’s disease and its treatment. Current Protein & Peptide Science, 15(7):673-80. doi: 10.2174/1389203715666140901103205 | PubMed
  • Ferraro, L.; Beggiato, S.; Borroto-Escuela D. O.; Ravani, L.; O’Connor W. T.; Tomasini, M. C.; Borelli, A. C.; Agnati, L. F.; Antonelli, T.; Tanganelli, S.; Fuxe, K. (2014) Neurotensin NTS1-dopamine D2 receptor-receptor interactions in putative receptor heteromers: relevance for Parkinson’s disease and schizophrenia. Current Protein & Peptide Science, 15(7):681-90. doi: 10.2174/1389203715666140901105253 | PubMed
  • Ferrante, A.; Martire, A.; Pepponi, R.; Varani, K.; Vincenzi, F.; Ferraro, L.; Beggiato, S.; Tebano, M. T.; Popoli, P. (2014)  Expression, pharmacology and functional activity of adenosine A1 receptors in genetic models of Huntington’s disease. Neurobiology of Disease,  71:193-204. doi: 10.1016/j.nbd.2014.08.013 | PubMed
  • Dalpiaz, A.; Ferraro, L.; Perrone, D.; Leo, E.; Iannuccelli, V.; Pavan, B.; Paganetto, G.; Beggiato, S.; Scalia, S. (2014) Brain uptake of a Zidovudine prodrug after nasal administration of solid lipid microparticles. Molecular Pharmaceutics, 11(5):1550-61. doi: 10.1021/mp400735c | PubMed
  • Beggiato, S.; Tanganelli, S.; Fuxe, K.; Antonelli, T.; Schwarcz, R.; Ferraro, L. (2014) Endogenous kynurenic acid regulates extracellular GABA levels in the rat prefrontal cortex. Neuropharmacology, 82:11-8. doi: 10.1016/j.neuropharm.2014.02.019 | PubMed
  • Zamberletti, E.; Beggiato, S.; Steardo, L Jr.; Prini, P.; Antonelli, T.; Ferraro, L.; Rubino, T.; Parolaro, D. (2014) Alterations of prefrontal cortex GABAergic transmission in the complex psychotic-like phenotype induced by adolescent delta-9-tetrahydrocannabinol exposure in rats. Neurobiology of Disease, 63:35-47. doi: 10.1016/j.nbd.2013.10.028 | PubMed

2013

  • Guidi, S.; Stagni, F.; Bianchi, P.; Ciani, E.; Ragazzi, E.; Trazzi, S.; Grossi, G.; Mangano, C.; Calzà, L.; Bartesaghi, R. (2013) Early pharmacotherapy with fluoxetine rescues dendritic pathology in the Ts65Dn mouse model of Down syndrome. Brain Pathology,
    3(2):129-43. doi: 10.1111/j.1750-3639.2012.00624.x | PubMed
  • Imbimbo, B. P.; Frigerio, E.; Breda, M.; Fiorentini, F.; Fernandez, M.; Sivilia, S.; Giardino, L.; Calzà, L.; Norris, D.; Casula, D.; Shenouda, M. (2013) Pharmacokinetics and pharmacodynamics of CHF5074 after short-term administration in healthy subjects. Alzheimer Disease and Associated Disorders,
    27(3):278-86. doi: 10.1097/WAD.0b013e3182622ace | PubMed
  • Giuliani, A.; Beggiato, S.; Baldassarro, A. V.; Mangano, C.; Giardino, L.; Imbimbo, B. P.; Antonelli, T.; Calzà, L.; Ferraro, L. (2013) CHF5074 restores visual memory ability and presynaptic cortical acetylcholine release in pre-plaque Tg2576 mice. Journal of Neurochemistry, 124(5):613-20. doi: 10.1111/jnc.12136 | PubMed
  • Salvati, S.; Di Biase, A.; Attorri, L.; Di Benedetto, R.; Sanchez, M.; Lorenzini, L.; Alessandri, M.; Calzà, L. (2013)
    Ethyl-eicosapentaenoic acid ameliorates the clinical course of experimental allergic encephalomyelitis induced in dark agouti rats. The Journal of Nutritional Biochemistry, 24(9):1645-54.
    doi: 10.1016/j.jnutbio.2013.02.005 | PubMed 
  • Brandi, G.; de Rosa F.; Calzà, L.; Girolamo, S. D.; Tufoni, M.; Ricci, C. S.; Cirignotta, F.; Caraceni, P.; Biasco, G. (2013) Can the tyrosine kinase inhibitors trigger metabolic encephalopathy in cirrhotic patients? Liver International, 33(3):488-93. doi: 10.1111/liv.12102 | PubMed 
  • Guidi, S.; Stagni, F.; Bianchi, P.; Ciani, E.; Ragazzi, E.; Trazzi, S.; Grossi, G.; Mangano, C.; Calzà, L.; Bartesaghi, R. (2013) Pharmacotherapy with fluoxetine restores functional connectivity from the dentate gyrus to field CA3 in the Ts65Dn mouse model of down syndrome. PLoS One, 8(4):e61689. doi: 10.1371/journal.pone.0061689 | PubMed
  • Sivilia, S.; Lorenzini, L.; Giuliani, A.; Gusciglio, M.; Fernandez, M.; Baldassarro, V. A.; Mangano, C.; Ferraro, L.; Pietrina, V.; Baroc, M. F.; Viscomi, R.; Ottonello, S.; Villetta, G.; Imbimbo, B. P.; Calzà, L.; Giardino, L. (2013) Multi-target action of the novel anti-Alzheimer compound CHF5074: in vivo study of long term treatment in Tg2576 mice. BMC Neuroscience, 14:44. doi: 10.1186/1471-2202-14-44 | PubMed
  • Ross, J.; Sharma, S.; Winston, J.; Nunez, M.; Bottini, G.; Franceschi, M.; Scarpini, E.; Frigerio, E.; Fiorentini, F.; Fernandez, M.; Sivilia, S.; Giardino, L.; Calzà, L.; Norris, D.; Cicirello, H.; Casula, D.; Imbimbo, B. P. (2013) CHF5074 reduces biomarkers of neuroinflammation in patients with mild cognitive impairment: a 12-week, double-blind, placebo-controlled study. Current Alzheimer Research, 10(7):742-53. doi: 10.2174/13892037113149990144 | PubMed
  • Calzà, L.; Baldassarro, V. A.; Giuliani, A.; Lorenzini, L.; Fernandez, M.; Mangano, C.; Sivilia, S.; Alessandri, M.; Gusciglio, M.; Torricella, R.; Giardino, L. (2013) From the multifactorial nature of Alzheime’s disease to multitarget therapy: the contribution of the translational approach. Current Topics in Medicinal Chemistry, 13(15):1843-52. doi: 10.2174/15680266113139990140 | PubMed
  • Alessandri, M.; Lizzo, G.; Gualandi, C.; Mangano, C.; Giuliani, A.; Focarete, M.L.; Calzà, L. (2013) Influence of biological matrix and artificial electrospun scaffolds on proliferation, differentiation and trophic factor synthesis of rat embryonic stem cells. Matrix Biology, 33:68-76. doi: 10.1016/j.matbio.2013.08.001 | PubMed 
  • Baldassarro, V. A.; Lizzo, G.; Paradisi, M.; Fernandez, M.; Giardino, L.; Calzà, L. (2013) Neural stem cells isolated from amyloid precursor protein-mutated mice: a tool for in vitro studies and drug discovery. Word Journal on Stem Cells,
    5(4):229-37. doi: 10.4252/wjsc.v5.i4.229 | PubMed
  • Pori, M.; Galletti, P.; Soldati, R.; Calzà, L.; Mangano, C.; Giacomini D. (2013) Azetidinone-retinoid hybrids: synthesis and differentiative effects. European Journal of Medicinal Chemistry,
    70:857-63. doi: 10.1016/j.ejmech.2013.09.057 | PubMed
  • Guidi, S.; Stagni, F.; Bianchi, P.; Ciani, E.; Giacomini, A.; De Franceschi, M.; Moldrich, R.; Kurniawan, N.; Mardon, K.; Giuliani, A., Calzà, L.; Bartesaghi, R. (2013) Prenatal pharmacotherapy rescues brain development in a Down syndrome model. Brain, 137(Pt 2):380-401. doi: 10.1093/brain/awt340 | PubMed 
  • Dolci, L. S.; Quiroga, S. D.; Gherardi, M.; Laurita, R.; Liguori, A.; Ghedini, E.; Sanibondi, P.; Fiorani, A.; Calzà, L.; Colombo, V.; Focarete, M. L. (2013) Carboxyl surface functionalization of poly(L-lactic acid) electrospun nanofibers through atmospheric non-thermal plasma affects fibroblast morphological response. Plasma Processes and Polymers 2014, doi.org/10.1002/ppap.201300104 | Wiley
  • Zaniboni, A.; Bernardini, C.; Alessandri, M.; Mangano, C.; Zannoni, A.; Bianchi, F.; Sarli, G.; Calzà, L.; Bacci, M. L.; Forni, M. (2013) Cells derived from porcine aorta tunica media show mesenchymal stromal-like cell properties in in vitro culture. American Journal of Physiology. Cell Physiology,
    306(4):C322-33. doi: 10.1152/ajpcell.00112.2013 | PubMed

2012

  • Dell’Acqua, M.L.; Lorenzini, L.; D’Intino, G.; Sivilia, S.; Pasqualetti, P.; Panetta, V.; Paradisi, M.; Filippi, M. M.; Baiguera, C.; Pizzi, M.; Giardino, L.; Rossini, P. M.; Calzà, L. (2012) Functional and molecular evidence of myelin- and neuroprotection by thyroid hormone administration in experimental allergic encephalomyelitis. Neuropathology and Applied Neurobiology,  38(5):454-70. doi: 10.1111/j.1365-2990.2011.01228.x | PubMed
  • Ferraro, L.; Beggiato, S.; Tomasini, M. C.; Fuxe, K.; Antonelli, T.; Tanganelli, S. (2012) A(2A)/D(2) receptor heteromerization in a model of Parkinson’s disease. Focus on striatal aminoacidergic signaling. Brain Research, 1476:96-107. doi: 10.1016/j.brainres.2012.01.032 | PubMed 
  • Ferraro, L.; Frankowska, M.; Marcellino, D.; Zaniewska, M.; Beggiato, S.; Filip, M.; Tomasini, M. C.; Antonelli, T.; Tanganelli, S.; Fuxe, K. (2012) A novel mechanism of cocaine to enhance dopamine d2-like receptor mediated neurochemical and behavioral effects. An in vivo and in vitro study. Neuropsychopharmacology, 37(8):1856-66. doi: 10.1038/npp.2012.33 | PubMed
  • Frye, C. A.; Bo, E.; Calamandrei, G.; Calzà, L.; Dessì-Fulgheri, F.; Fernández, M.; Fusani, L.; Kah, O.; Kajta, M.; Le Page, Y.; Patisaul, H. B.; Venerosi, A.; Wojtowicz, A. K.; Panzica, G. C. (2012) Endocrine disrupters: a review of some sources, effects, and mechanisms of actions on behaviour and neuroendocrine systems. Journal of Neuroendocrinology, 24(1):144-59. doi: 10.1111/j.1365-2826.2011.02229.x | PubMed
  • Massella, A.; D’Intino, G.; Fernández, .;, Sivilia, S.; Lorenzini, L.; Giatti, S.; Melcangi, R. C.; Calzà, L.; Giardino, L. (2012) Gender effect on neurodegeneration and myelin markers in an animal model for multiple sclerosis. BMC Neuroscience, 13:12. doi: 10.1186/1471-2202-13-12 | PubMed
  • Tanganelli, S.; Antonelli, T.; Tomasini, M. C.; Beggiato, S.; Fuxe, K.; Ferraro, L. (2012) Relevance of dopamine D(2)/neurotensin NTS1 and NMDA/neurotensin NTS1 receptor interaction in psychiatric and neurodegenerative disorders. Current Medical Chemistry, 19(3):304-16. doi: 10.2174/092986712803414268 | PubMed 
  • Tomasini, M. C.; Beggiato, S.; Ferraro, L.; Tanganelli, S.; Marani, L.; Lorenzini, L.; Antonelli, T. (2012) Prenatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin produces alterations in cortical neuron development and a long-term dysfunction of glutamate transmission in rat cerebral cortex. Neurochemistry International, 61(5):759-66. doi: 10.1016/j.neuint.2012.07.004 | PubMed

2011

  • Boero, C.; Carrara, S.; Del Vecchio, G.; Calzà, L.; De Micheli, G. (2011) Highly sensitive carbon nanotube-based sensing for lactate and glucose monitoring in cell culture. IEEE Transactions on NanoBioscience, 10(1):59-67. doi: 10.1109/TNB.2011.2138157 | PubMed
  • D’Intino, G.; Lorenzini, L.; Fernandez, M.; Taglioni, A.; Perretta, G.; Del Vecchio, G.; Villoslada, P.; Giardino, L.; Calzà, L. (2011) Triiodothyronine administration ameliorates the demyelination/remyelination ratio in a non-human primate model of multiple sclerosis by correcting tissue hypothyroidism. Journal of Neuroendocrinology, 23(9):778-90. doi: 10.1111/j.1365-2826.2011.02181.x | PubMed
  • Baratto, L.; Calzà, L.; Capra, R.; Gallamini, M.; Giardino, L.; Giuliani, A.; Lorenzini, L.; Traverso, S. (2011) Ultra-low-level laser therapy. Lasers in Medical Science, 26(1):103-12. doi: 10.1007/s10103-010-0837-2 | PubMed
  • Colombo, G.; Lorenzini, L.; Zironi, E.; Galligioni, V.; Sonvico, F.; Balducci, A. G.; Pagliuca, G.; Giuliani, A.; Calzà, L.; Scagliarini, A. (2011) Brain distribution of ribavirin after intranasal administration. Antiviral Research, 92(3):408-14. doi: 10.1016/j.antiviral.2011.09.012 | PubMed 
  • Balducci, C.; Mehdawy, B.; Mare, L.; Giuliani, A.; Lorenzini, L.; Sivilia, S; Giardino, L.; Calzà, L.; Lanzillotta, A.; Sarnico, I.; Pizzi, M.; Usiello, A.; Viscomi, A. R.; Ottonello, S.; Villetti, G.; Imbimbo, B. P.; Nisticò, G.; Forloni, G.; Nisticò, R. (2011) The γ-secretase modulator CHF5074 restores memory and hippocampal synaptic plasticity in plaque-free Tg2576 mice. Journal of Alzheimer’s Disease, 24(4):799-816. doi: 10.3233/JAD-2011-101839 | PubMed
  • Frye, C. A.; Bo, E., Calamandrei, G.; Calzà, L.; Dessì-Fulgheri, F.; Fernández, M.; . . . (2011) Endocrine disrupters: a review of some sources, effects, and mechanisms of actions on behaviour and neuroendocrine systems. Journal of Neuroendocrinology, 24(1):144-59. doi: 10.1111/j.1365-2826.2011.02229.x | PubMed
  • Fernández, M.; Pirondi, S.; Chen, B. L.; Del Vecchio, G.; Alessandri, M.; Farnedi, A.; Pession, A.; Feki, A.;  Jaconi, M. E.; Calzà, L. (2011) Isolation of rat embryonic stem-like cells: a tool for stem cell research and drug discovery. Developmental Dynamics, 40(11):2482-94. doi: 10.1002/dvdy.22761 | PubMed
  • Ferraro, L.; Beggiato, S.; Tomasini, M. C.; Antonelli, T.; Loche, A.; Tanganelli, S. (2011) GET73 modulates rat hippocampal glutamate transmission: evidence for a functional interaction with mGluR5. Pharmacological Reports, 63(6):1359-71. doi: 10.1016/s1734-1140(11)70700-9 | PubMed
  • Ferraro, L.; Beggiato, S.; Tomasini, M. C.; Fuxe, K.; Tanganelli, S.; Antonelli, T. (2011) Neurotensin regulates cortical glutamate transmission by modulating N-methyl-D-aspartate receptor functional activity: an in vivo microdialysis study. Journal of Neuroscience Research, 89(10):1618-26. doi: 10.1002/jnr.22686 | PubMed

2010

  • Calzà, L.; Fernandez, M.; Giardino, L. (2010) Cellular approaches to central nervous system remyelination stimulation: thyroid hormone to promote myelin repair via endogenous stem and precursor cells. Journal of Molecular Endocrinology, 44(1):13-23. doi: 10.1677/JME-09-0067 | PubMed
  • Castaldo, P.; Magi, S.; Cataldi, M.; Arcangeli, S.; Lariccia, V.; Nasti, A. A.; Ferraro, L.; Tomasini, M. C.; Antonelli, T.; Cassano, T.; Cuomo, V.; Amoroso, S. (2010) Altered regulation of glutamate release and decreased functional activity and expression of GLT1 and GLAST glutamate transporters in the hippocampus of adolescent rats perinatally exposed to Delta(9)-THC. Pharmacological Research, 61(4):334-41. doi: 10.1016/j.phrs.2009.11.008 | PubMed 
  • Fernández, M.; Paradisi, M.; D’Intino, G.; Del Vecchio, G.; Sivilia, S.; Giardino, L.; Calzà, L. (2010) A single prenatal exposure to the endocrine disruptor 2,3,7,8-tetrachlorodibenzo-p-dioxin alters developmental myelination and remyelination potential in the rat brain. Journal of Neurochemistry, 115(4):897-909. doi: 10.1111/j.1471-4159.2010.06974.x | PubMed 
  • Ferraro, L.; Beggiato, S.; Marcellino, D.; Frankowska, M.; Filip, M.; Agnati, L. F.; Antonelli, T.; Tomasini, M. C.; Tanganelli, S.; Fuxe, K. (2010) Nanomolar concentrations of cocaine enhance D2-like agonist-induced inhibition of the K+-evoked [3H]-dopamine efflux from rat striatal synaptosomes: a novel action of cocaine. Journal of Neural Transmission, 117(5):593-7. doi: 10.1007/s00702-010-0389-4 | PubMed
  • Imbimbo, B. P.; Giardino, L.; Sivilia, S.; Giuliani, A.; Gusciglio, M.; Pietrini, V.; Del Giudice, E.; D’Arrigo, A.; Leon, A.; Villetti, G.; Calzà, L .(2010) CHF5074, a novel gamma-secretase modulator, restores hippocampal neurogenesis potential and reverses contextual memory deficit in a transgenic mouse model of Alzheimer’s disease. Journal of Alzheimer’s Disease, (1):159-73. doi: 10.3233/JAD-2010-1366 | PubMed
  • Lorenzini, L.; Giuliani, A.; Giardino, L.; Calzà, L. (2010) Laser acupuncture for acute inflammatory, visceral and neuropathic pain relief: An experimental study in the laboratory rat. Research in Veterinary Science, 88(1):159-65. doi: 10.1016/j.rvsc.2009.06.001 | PubMed
  • Paradisi, M.; Fernández, M.; Del Vecchio, G.; Lizzo, G.; Marucci, G.; Giulioni, M.; Pozzati, E.; Antonelli, T.; Lanzoni, G.; Bagnara, G. P.; Giardino, L.; Calzà, L. (2010) Ex vivo study of dentate gyrus neurogenesis in human pharmacoresistant temporal lobe epilepsy. Neuropathology and Applied Neurobiology, 36(6):535-50. doi: 10.1111/j.1365-2990.2010.01102.x | PubMed

2009

  • Del Vecchio G, Giuliani A, Fernandez M, Mesirca P, Bersani F, Pinto R, Ardoino L, Lovisolo GA, Giardino L, Calzà L (2009) Effect of radiofrequency electromagnetic field exposure on in vitro models of neurodegenerative disease. Bioelectromagnetics30:564-72. • PubMed
  • Del Vecchio G, Giuliani A, Fernandez M, Mesirca P, Bersani F, Pinto R, Ardoino L, Lovisolo GA, Giardino L, Calzà L (2009) Continuous exposure to 900MHz GSM-modulated EMF alters morphological maturation of neural cells. Lett.455:173-7. • PubMed
  • Fernández M, Paradisi M, Del Vecchio G, Giardino L, Calzà L (2009) Thyroid hormone induces glial lineage of primary neurospheres derived from non-pathological and pathological rat brain: implications for remyelination-enhancing therapies. J. Dev. Neurosci. 27:769-78. • PubMed
  • Ferraro L, Tomasini MC, Beggiato S, Guerrini R, Salvadori S, Fuxe K, Calzà L, Tanganelli S, Antonelli T (2009) Emerging evidence for neurotensin receptor 1 antagonists as novel pharmaceutics in neurodegenerative disorders. Mini Rev Med Chem 9:1429-38. • PubMed
  • Giuliani A, Lorenzini L, Gallamini M, Massella A, Giardino L, Calzà L (2009) Low infra red laser light irradiation on cultured neural cells: effects on mitochondria and cell viability after oxidative stress. BMC Complement Altern Med 9:8. • PubMed
  • Massella, A.; Gusciglio, M.; D’Intino, G.; Sivilia, S.; Ferraro, L.; Calzà, L.; Giardino, L. (2009) Gabapentin treatment improves motor coordination in a mice model of progressive ataxia. Brain Research, 1301:135-42. doi: 10.1016/j.brainres.2009.09.004 | PubMed

2008

  • Ferraro, L.; Tomasini, M. C.; Mazza, R.; Fuxe, K.; Fournier, J.; Tanganelli, S.; Antonelli, T. (2008) Neurotensin receptors as modulators of glutamatergic transmission. Brain Research Reviews, 58(2):365-73. doi: 10.1016/j.brainresrev.2007.11.001 | PubMed
  • Sivilia, S.; Giuliani, A.; Del Vecchio, G.; Giardino, L.; Calzà, L. (2008) Age-dependent impairment of hippocampal neurogenesis in chronic cerebral hypoperfusion. Neuropathology and Applied Neurobiology, 34(1):52-61. doi: 10.1111/j.1365-2990.2007.00863.x | PubMed 
  • Sivilia, S.; Paradisi, M.; D’Intino, G.; Fernandez, M.; Pirondi, S.; Lorenzini, L.; Calzà, L. (2008) Skin homeostasis during inflammation: a role for nerve growth factor. Histology and Histopathology, 23(1):1-10. doi: 10.14670/HH-23.1 | PubMed

2007

  • Antonelli, T.; Fuxe, K.; Tomasini, M. C.; Mazzoni, E.; Agnati, L. F.; Tanganelli, S.; Ferraro, L. (2007) Neurotensin receptor mechanisms and its modulation of glutamate transmission in the brain: relevance for neurodegenerative diseases and their treatment. Progress in Neurobiology, 83(2):92-109. doi: 10.1016/j.pneurobio.2007.06.006 | PubMed
  • Antonelli, T.; Tomasini, M. C.; Fuxe, K.; Agnati ,L. F.; Tanganelli, S.; Ferraro, L. (2007) Receptor-receptor interactions as studied with microdialysis. Focus on NTR/D2 interactions in the basal ganglia. Journal of Neurotransmission, 114(1):105-13. doi: 10.1007/s00702-006-0558-7 | PubMed
  • Emgård, M.; Paradisi, M.; Pirondi, S.; Fernandez, M.; Giardino, L.; Calzà, L. (2007) Prenatal glucocorticoid exposure affects learning and vulnerability of cholinergic neurons. Neurobiology of Aging, 28(1):112-21. doi: 10.1016/j.neurobiolaging.2005.11.015 | PubMed 
  • Pirondi, S.; D’Intino, G.; Gusciglio, M.; Massella, A.; Giardino, L.; Kuteeva, E.; Ogren, S. O.; Hökfelt, T.; Calzà, L. (2007) Changes in brain cholinergic markers and spatial learning in old galanin-overexpressing mice. Brain Research, 1138:10-20. doi: 10.1016/j.brainres.2006.12.069 | PubMed

2006

  • Antonelli, T.; Fuxe, K.; Agnati, L.; Mazzoni, E.; Tanganelli, S.; Tomasini, M. C.; Ferraro, L. (2006) Experimental studies and theoretical aspects on A2A/D2 receptor interactions in a model of Parkinson’s disease. Relevance for L-dopa induced dyskinesias. Journal of the Neurological Sciences, 248(1-2):16-22. doi: 10.1016/j.jns.2006.05.019 | PubMed
  • D’Intino, G.; Perretta, G.; Taglioni, A.; Calistri, M.; Falzone, C.; Baroni, M.; Giardino, L.; Calzà, L. (2006) Endogenous stem and precursor cells for demyelinating diseases: an alternative for transplantation? Neurological Research, 28(5):513-7. doi: 10.1179/016164106X116773 | PubMed

2005

  • Antonelli, T.; Fuxe, K.; Tomasini, M. C.; Bartoszyk, G. D.; Seyfried, C. A.; Tanganelli, S.; Ferraro, L. (2005) Effects of sarizotan on the corticostriatal glutamate pathways. Synapse, 58(3):193-9. doi: 10.1002/syn.20195 | PubMed
  • Calzà, L.; Fernandez, M.; Giuliani, A.; D’Intino, G.; Pirondi, S.; Sivilia, S.; Paradisi, M.; Desordi, N.; Giardino, L. (2005) Thyroid hormone and remyelination in adult central nervous system: a lesson from an inflammatory-demyelinating disease. Brain Research Reviews, 48(2):339-46. doi: 10.1016/j.brainresrev.2004.12.022 | PubMed 
  • D’Intino, G.; Paradisi, M.; Fernandez, M.; Giuliani, A.; Aloe, L.; Giardino, L.; Calzà, L. (2005) Cognitive deficit associated with cholinergic and nerve growth factor down-regulation in experimental allergic encephalomyelitis in rats. Proceedings of the National Academy of Sciences, 102(8):3070-5. doi: 10.1073/pnas.0500073102 | PubMed
  • Fernandez, M.; Pirondi, S.; Antonelli, T.; Ferraro, L.; Giardino, L.; Calzà, L, (2005) Role of c-Fos protein on glutamate toxicity in primary neural hippocampal cells. Journal of Neuroscience Research, 82(1):115-25. doi: 10.1002/jnr.20608 | PubMed
  • Pirondi, S.; Fernandez, M.; Schmidt, R.; Hökfelt, T.; Giardino, L.; Calzà, L. (2005) The galanin-R2 agonist AR-M1896 reduces glutamate toxicity in primary neural hippocampal cells. Journal of Neurochemistry, 95(3):821-33. doi: 10.1111/j.1471-4159.2005.03437.x | PubMed 
  • Pirondi, S.; Kuteeva, E.; Giardino, L.; Ferraro, L.; Antonelli, T.; Bartfai, T.; Ogren, S. O.; Hökfelt, T.; Calzà, L. (2005) Behavioral and neurochemical studies on brain aging in galanin overexpressing mice. Neuropeptides, 39(3):305-12. doi: 10.1016/j.npep.2005.02.006 | PubMed 

2004

  • Antonelli, T.; Ferraro, L.; Fuxe, K.; Finetti, S.; Fournier, J.; Tanganelli, S.; De Mattei, M.; Tomasini, M. C. (2004) Neurotensin enhances endogenous extracellular glutamate levels in primary cultures of rat cortical neurons: involvement of neurotensin receptor in NMDA induced excitotoxicity. Cerebral Cortex, 14(4):466-73. doi: 10.1093/cercor/bhh008 | PubMed
  • Calzà, L.; Fernandez, M.; Giuliani, A.; Pirondi, S.; D’Intino, G.; Manservigi, M.; De Sordi, N.; Giardino, L. (2004) Stem cells and nervous tissue repair: from in vitro to in vivo. Progress in Brain Research. 146:75-91. doi: 10.1016/s0079-6123(03)46005-6 | PubMed 
  • Calzà, L.; Giardino, L. (2004) Neuroprotection: a realistic goal for aged brain? Advances in Experimental Medicine and Biology. 541:153-68. doi: 10.1007/978-1-4419-8969-7_9 | PubMed 
  • Fernandez, M.; Giuliani, A.; Pirondi, S.; D’Intino, G.; Giardino, L.; Aloe, L.; Levi-Montalcini, R.; Calzà, L. (2004) Thyroid hormone administration enhances remyelination in chronic demyelinating inflammatory disease. Proceedings of the National Academy of Sciences, 101(46):16363-8. doi: 10.1073/pnas.0407262101 | PubMed 
  • Fernandez, M.; Pirondi, S.; Manservigi, M.; Giardino, L.; Calzà, L. (2004) Thyroid hormone participates in the regulation of neural stem cells and oligodendrocyte precursor cells in the central nervous system of adult rat. The European Journal of Neuroscience, 20(8):2059-70. doi: 10.1111/j.1460-9568.2004.03664.x | PubMed
  • Giardino, L.; Giuliani, A.; Fernandez, M.; Calzà, L (2004) Spinal motoneurone distress during experimental allergic encephalomyelitis. Neuropathology and Applied Neurobiology, 30(5):522-31. doi: 10.1111/j.1365-2990.2004.00559.x | PubMed
  • Giuliani, A.; D’Intino, G.; Paradisi, M.; Giardino, L.; Calzà, L. (2004) p75(NTR)-immunoreactivity in the subventricular zone of adult male rats: expression by cycling cells. Journal of Molecular Histology, 35(8-9):749-58. doi: 10.1007/s10735-004-9609-2 | PubMed
  • Giuliani, A.; Fernandez, M.; Farinelli, M.; Baratto, L.; Capra, R.; Rovetta, G.; Monteforte, P.; Giardino, L.; Calzà, L. (2004) Very low level laser therapy attenuates edema and pain in experimental models. International Journal of Tissue Reactions, 26(1-2):29-37 | PubMed
  • Tanganelli, S.; Sandager Nielsen, K.; Ferraro, L.; Antonelli, T.; Kehr, J.; Franco, R.; Ferré, S.; Agnati, L. F.; Fuxe, K.; Scheel-Krüger, J. (2004) Striatal plasticity at the network level. Focus on adenosine A2A and D2 interactions in models of Parkinson’s Disease. Parkinsonism & Related Disorders, 10(5):273-80. doi: 10.1016/j.parkreldis.2004.02.015 | PubMed 

2003

  • Calzà, L.; Fernandez, M.; Giuliani, A.; Pirondi, S.; D’Intino, G.; Giardino, L. (2003) Nerve growth factor in the central nervous system: more than neuron survival. Archives italiennes de biologie, 141(2-3):93-102 | PubMed
  • Calza, L.; Giuliani, A.; Fernandez, M.; Pirondi, S.; D’Intino, G.; Aloe, L.; Giardino, L. (2003) Neural stem cells and cholinergic neurons: regulation by immunolesion and treatment with mitogens, retinoic acid, and nerve growth factor. Proceedings of the National Academy of Sciences, 100(12):7325-30. doi: 10.1073/pnas.1132092100 | PubMed

2002

  • Antonelli, T.; Tomasini, M. C.; Finetti, S.; Giardino, L.; Calzà, L.; Fuxe, K.; Soubriè, P.; Tanganelli, S.; Ferraro, L. (2002) Neurotensin enhances glutamate excitotoxicity in mesencephalic neurons in primary culture. Journal of Neuroscience Research,
    70(6):766-73. doi: 10.1002/jnr.10415 | PubMed
  • Calza, L.; Fernandez, M.; Giuliani, A.; Aloe, L.; Giardino, L. (2002) Thyroid hormone activates oligodendrocyte precursors and increases a myelin-forming protein and NGF content in the spinal cord during experimental allergic encephalomyelitis. Proceedings of the National Academy of Sciences,
    99(5):3258-63. doi: 10.1073/pnas.052704499 | PubMed
  • Díaz-Cabiale, Z.; Fuxe, K.; Narváez, J.A.; Finetti, S.; Antonelli, T.; Tanganelli, S.; Ferraro, L. (2002) Neurotensin-induced modulation of dopamine D2 receptors and their function in rat striatum: counteraction by a NTR1-like receptor antagonist. Neuroreport, 13(6):763-6. doi: 10.1097/00001756-200205070-00006 | PubMed
  • Giardino, L.; Giuliani, A.; Battaglia, A.; Carfagna, N.; Aloe, L.; Calza’, L. (2002) Neuroprotection and aging of the cholinergic system: a role for the ergoline derivative nicergoline (Sermion). Neuroscience, 09(3):487-97. doi: 10.1016/s0306-4522(01)00470-5 | PubMed
  • Giardino, L.; Giuliani, A.; Bettelli, C.; Calzà, L. (2002) Thyroid hormone and retinoids affect motoneuron phenotype and reaction after axotomy in the spinal cord of adult rats. Brain Research, 925(2):122-32. doi: 10.1016/s0006-8993(01)03266-8 | PubMed 
  • Giardino, L.; Zanni, M.; Fernandez, M.; Battaglia, A.; Pignataro, O.; Calzà, L. (2002) Plasticity of GABA(a) system during ageing: focus on vestibular compensation and possible pharmacological intervention. Brain Research, 929(1):76-86. doi: 10.1016/s0006-8993(01)03381-9 | PubMed

2001

  • Ferraro, L.; Tomasini, M. C.; Fernandez, M.; Bebe B. W.; O’Connor W. T.; Fuxe, K.; Glennon, J. C.; Tanganelli, S.; Antonelli, T. (2001) Nigral neurotensin receptor regulation of nigral glutamate and nigroventral thalamic GABA transmission: a dual-probe microdialysis study in intact conscious rat brain. Neuroscience, 102(1):113-20. doi: 10.1016/s0306-4522(00)00448-6 | PubMed

2000

  • Giardino, L.; Bettelli, C.; Calzà, L. (2000) In vivo regulation of precursor cells in the subventricular zone of adult rat brain by thyroid hormone and retinoids. Neuroscience Letters, 295(1-2):17-20. doi: 10.1016/s0304-3940(00)01580-9 | PubMed
  • Giardino, L.; Giuliani, A.; Calzà, L. (2000) Exogenous administration of L-arginine protects cholinergic neurons from colchicine neurotoxicity. Neuroreport, 11(8):1769-72. doi: 10.1097/00001756-200006050-00034 | PubMed
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