Luciana Giardino and Laura Calzà, president and scientific director of IRET, started their first research group in 1984.
In 1987 they created the Center of Physiopathology of the Nervous System at the Hesperia Hospital in Modena.
In 1999 the research group moved to the University of Bologna and the Center of Physiopathology of the Nervous System became a member of DIMORFIPA, University of Bologna.
In February 2006 IRET Foundation was started and Mr. Ezio Baldazzi donated 10.000 sqm of land in Ozzano dell’Emilia, on which in 2012 the research laboratories were built
IRET has signed an agreement with the Center for Industrial Research, University of Bologna, and the University of Ferrara through the Department of Clinical and Experimental Medicine, Section of Pharmacology, and the Department of Life Sciences and Biotechnology. IRET has also signed an agreement with the Istituto Rinaldi Fontani in Florence.